{
  "cohort": {
    "groups": {
      "Control": 5,
      "sALS": 5
    },
    "purpose": "Technical workflow example; not biological or clinical validation.",
    "sample_aliases": [
      "Control_1",
      "Control_2",
      "Control_3",
      "Control_4",
      "Control_5",
      "sALS_1",
      "sALS_2",
      "sALS_3",
      "sALS_4",
      "sALS_5"
    ]
  },
  "differential": {
    "dmr_rows": 88917,
    "dmr_rows_q_lt_0_05": 1026,
    "modalities": [
      "cpg",
      "occupancy",
      "wps"
    ],
    "pca_sample_count": 10
  },
  "fragmentomics": {
    "cleavage": "not_run",
    "delfi_numeric_values": 5340345,
    "delfi_samples": 10,
    "end_motif_samples": 10,
    "occupancy_matrix_rows": 437869,
    "scope": {
      "bins_count": 538712,
      "mode": "panel",
      "note": "Targeted-panel mode restricts WPS, occupancy, and DELFI to reads and intervals overlapping the configured target BED; these outputs are not genome-wide measurements.",
      "target_sha256": "82f54b6e17d92c98e07e9204cddeffad9bd4b7882e925e123954013b33b65398"
    },
    "wps_matrix_rows": 437869
  },
  "mesa": {
    "interpretation": "Technical workflow output only; not model performance validation.",
    "loocv_auc": {
      "Multimodal": 0.7600000000000001,
      "cpg": 0.36,
      "occupancy": 0.8200000000000001,
      "wps": 0.8
    },
    "sample_count": 10,
    "screening_best_auc": {
      "cpg": 0.7733,
      "occupancy": 1.0,
      "wps": 1.0
    }
  },
  "report": {
    "html_present": true,
    "html_size_bytes": 13557653,
    "sections_discovered": {
      "Differential / DMR": true,
      "Fragmentomics": true,
      "MESA": true,
      "Processing": true,
      "cfDNA QC": true
    }
  },
  "schema_version": 1
}